Blar i forfatter "Calvignac-Spencer, Sébastien"

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    • Identification of a Novel Human Polyomavirus in Organs of the Gastrointestinal Tract 

      Korup, Sarah; Rietscher, Janita; Calvignac-Spencer, Sébastien; Trusch, Franziska; Hofmann, Jörg; Moens, Ugo; Sauer, Igor; Voigt, Sebastien; Schmuck, Rosa; Ehlers, Bernhard (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Polyomaviruses are small, non-enveloped viruses with a circular double-stranded DNA genome. Using a generic polyomavirus PCR targeting the VP1 major structural protein gene, a novel polyomavirus was initially identified in resected human liver tissue and provisionally named Human Polyomavirus 12 (HPyV12). Its 5033 bp genome is predicted to encode large and small T antigens and the 3 structural ...

    • Novel Polyomaviruses of Nonhuman Primates: Genetic and Serological Predictors for the Existence of Multiple Unknown Polyomaviruses within the Human Population 

      Scuda, Nelly; Madinda, Nadege; Akoua-Koffi, Chantal; Adjogoua, Edgard V; Wevers, Diana; Hofmann, Jörg; Cameron, Kenneth M.; Leendertz, Siv Aina Jensen; Couacy-Hymann, Emmanuel; Robbins, Martha M.; Boesch, Christophe; Jarvis, Michael; Moens, Ugo; Calvignac-Spencer, Sébastien; Leendertz, Fabian H; Ehlers, Bernhard; Ehlers, B (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Polyomaviruses are a family of small non-enveloped DNA viruses that encode oncogenes and have been associated, to greater or lesser extent, with human disease and cancer. Currently, twelve polyomaviruses are known to circulate within the human population. To further examine the diversity of human polyomaviruses, we have utilized a combinatorial approach comprised of initial degenerate primer-based ...

    • A taxonomy update for the Family Polyomaviridae 

      Calvignac-Spencer, Sébastien; Feltkamp, Mariet CW; Daugherty, Matthew D; Moens, Ugo; Ramqvist, Torbjörn; Johne, Reimar; Ehlers, Bernhard (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-29)
      Many distinct polyomaviruses infecting a variety of vertebrate hosts have recently been discovered, and their complete genome sequence could often be determined. To accommodate this fast-growing diversity, the International Committee on Taxonomy of Viruses (ICTV) <i>Polyomaviridae</i> Study Group designed a host- and sequence-based rationale for an updated taxonomy of the family <i>Polyomaviridae</i>. ...